If you have gastrointestinal issues
NSAIDs not only irritate the lining of the stomach and intestines, but they can also reduce blood flow in the area and impair its ability to fix itself. So if you already have digestive issues, such as inflammatory bowel disease, you probably wouldn’t want to pop an Advil or Motrin or any other NSAID. They’re not effective for pain associated with IBD and, in the cases where you’re suffering from other achy issues, you’re better off talking to your doctor about alternative treatments. Acetaminophen may be a good option for headache pain, for instance. According to Venkata Yellepeddi, PhD, adjunct assistant professor in pharmaceutical chemistry the University of Utah, if you have trouble with menstrual cramping, birth control pills could help